Endocrine Abstracts

Background: Spondyloenchondrodysplasia (SPENCD) is a rare autosomal recessive skeletal dysplasia characterized by radiolucent spondylar and metaphyseal lesions, representing the persistence of chondroid tissue islands within the bone. Besides skeletal abnormalities and short stature, autoimmune disorders, including systemic lupus erythematosus, Sjögren’s syndrome, hemolytic anemia, thrombocytopenia, hypothyroidism, inflammatory myositis, Raynaud’s disease, and v...